Imatinib Mesylate

CAS number:

220127-57-1

Chemical Name:

4-[(4-methyl-1-piperazinyl) methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl] amino] phenyl]-benzamide, monomethanesulfonate.

Mechanism of action:

Tyrosine kinase inhibitor (specific for abnormal BCR-ABL tyrosine kinase produced by Philadelphia chromosome in CML/ALL)

Indications:

Acute lymphoblastic leukemia, Chronic myelogenous leukemia, Gastrointestinal stromal tumors, Dermatofibrosarcoma protuberans, Systemic mastocytosis.

Chemical Formula :