Sunitinib Malate

CAS number:

341031-54-7

 

Chemical Name:

N-[2-(Diethylamino) ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt.

 

Mechanism of action:                       

Multikinase inhibitor (VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET).

 

Indications:

Gastrointestinal Stromal Tumor (GIST), Advanced Renal Cell

Chemical Formula :